Flexible, Adaptive or Attractive Clinical Trial Design
نویسندگان
چکیده
منابع مشابه
Adaptive Clinical Trial Design
Adaptive design is usually defined as the use of accumulating data obtained during the conduct of the trial to decide how to modify aspects of the trial as it progresses, without affecting its validity and integrity (Gallo et al., 2006). This form of research design involves a prospectively planned opportunity to modify the parameters of the study based on analysis of interim data while the stu...
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O ne of the most talked-about cancer clinical trials last spring was BATTLE — a phase II trial that did not change practice or introduce a new drug. What got all the attention was the non-small cell lung cancer trial’s “adaptive” design. In adaptive trials, data gathered as the trial progresses are used to change some aspect of the trial midstream. These trials have increased over the past deca...
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ژورنال
عنوان ژورنال: Drug Designing: Open Access
سال: 2012
ISSN: 2169-0138
DOI: 10.4172/2169-0138.1000e104